Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625364 | 0.83 | LMNA (0.66) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL2072200 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HTTL3MBTL1LMNAKMT2A | |
| SCHEMBL7013152 | 0.82 | ALDH1A1 (0.76) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL3207417 | 0.82 | LMNA (0.64) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL29979179 | 0.82 | LMNA (0.64) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL6790086 | 0.81 | KMT2A (0.72) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL23412472 | 0.80 | POLB (0.65) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL18548983 | 0.80 | POLB (0.65) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL29846090 | 0.80 | POLB (0.65) | ALDH1A1HTTGAATHRBL3MBTL1 | |
| SCHEMBL3124112 | 0.80 | ALDH1A1 (0.66) | ALDH1A1HTTGAATHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149165-B2 | Coatings with molecular flexibility for ice adhesion mitigation | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) | 2021-10-19 | — | — | US | disclosed |
| US-10377916-B2 | Coatings with molecular flexibility for ice adhesion mitigation | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) | 2019-08-13 | — | — | US | disclosed |
| WO-2017040797-A1 | COATINGS WITH MOLECULAR FLEXIBILITY FOR ICE ADHESION MITIGATION | UNITED STATES OF AMERICAN as represented by THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20170058168-A1 | Coatings with Molecular Flexibility for Ice Adhesion Mitigation | U.S.A AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2017-03-02 | — | — | US | disclosed |