Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117517 | 1.00 | ALDH1A1 (0.66) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL4951837 | 0.94 | ALDH1A1 (0.73) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL9011397 | 0.91 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL3476585 | 0.91 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL3476172 | 0.91 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL4953010 | 0.91 | ALDH1A1 (0.61) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL6673456 | 0.91 | ALDH1A1 (0.61) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL3476080 | 0.91 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL8820191 | 0.91 | ALDH1A1 (0.57) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL10406550 | 0.91 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149165-B2 | Coatings with molecular flexibility for ice adhesion mitigation | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) | 2021-10-19 | — | — | US | disclosed |
| US-10377916-B2 | Coatings with molecular flexibility for ice adhesion mitigation | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) | 2019-08-13 | — | — | US | disclosed |
| WO-2017040797-A1 | COATINGS WITH MOLECULAR FLEXIBILITY FOR ICE ADHESION MITIGATION | UNITED STATES OF AMERICAN as represented by THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20170058168-A1 | Coatings with Molecular Flexibility for Ice Adhesion Mitigation | U.S.A AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2017-03-02 | — | — | US | disclosed |