Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18549333 | 0.87 | MAPT (0.65) | SMN1; SMN2MAPTLIN28ATDP1KDM4E | |
| SCHEMBL18549341 | 0.87 | MAPT (0.65) | SMN1; SMN2MAPTLIN28ATDP1KDM4E | |
| SCHEMBL825189 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLIN28ATDP1CHRM2 | |
| SCHEMBL18549343 | 0.83 | MAPT (0.58) | SMN1; SMN2MAPTLIN28ATDP1KDM4E | |
| SCHEMBL18563031 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTLIN28ATDP1KDM4E | |
| SCHEMBL29386417 | 0.77 | CHRM2 (0.66) | SMN1; SMN2MAPTLIN28ATDP1CHRM2 | |
| SCHEMBL18301491 | 0.77 | CHRM2 (0.66) | SMN1; SMN2MAPTLIN28ATDP1CHRM2 | |
| SCHEMBL18563030 | 0.77 | MAPT (0.61) | SMN1; SMN2MAPTLIN28ATDP1KDM4E | |
| SCHEMBL4274463 | 0.76 | CHRM2 (0.66) | SMN1; SMN2MAPTLIN28ATDP1CHRM2 | |
| SCHEMBL10607691 | 0.76 | CHRM2 (0.64) | SMN1; SMN2MAPTLIN28ATDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233205-B2 | Magnetic resonance imaging contrast agent capable of detecting hydrogen peroxide and reducing reactive oxygen species | AUBURN UNIVERSITY (US) | 2019-03-19 | — | — | US | disclosed |
| US-20170057986-A1 | MAGNETIC RESONANCE IMAGING CONTRAST AGENT CAPABLE OF DETECTING HYDROGEN PEROXIDE AND REDUCING REACTIVE OXYGEN SPECIES | NATIONAL SCIENCE FOUNDATION | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233205-B2 | Magnetic resonance imaging contrast agent capable of detecting hydrogen peroxide and reducing reactive oxygen species | PRDX3, GPX4, GPX1 | SMN1; SMN2 1007/4885MAPT 3042/4885LIN28A 4689/4885 |
| US-20170057986-A1 | MAGNETIC RESONANCE IMAGING CONTRAST AGENT CAPABLE OF DETECTING HYDROGEN PEROXIDE AND REDUCING REACTIVE OXYGEN SPECIES | PRDX3, GPX4, GPX1 | SMN1; SMN2 1007/4885MAPT 3042/4885LIN28A 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.