Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703887 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL12547367 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL854197 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL7805532 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL17512618 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL17512452 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL17512453 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6478813 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL29179883 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ALMNANPY2R | |
| SCHEMBL1856887 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324016-B1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INT (ES) | 2012-04-25 | — | — | EP | disclosed |
| EP-2324016-B1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INT (ES) | 2012-04-25 | — | — | EP | disclosed |
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | disclosed |
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | disclosed |
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | disclosed |
| EP-2324016-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Ferrer Internacional, S.A. (ES) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010000704-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010000704-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141162-A1 | 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141162-A1 | 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | OXA1L, MRPL21, RPL5 | ALDH1A1 1275/4885MAPT 4653/4885KMT2A 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.