Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240096 | 0.85 | MAPT (0.43) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL1854963 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL12469669 | 0.79 | MAPT (0.39) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL1856887 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1KMT2AHTT | |
| SCHEMBL30890308 | 0.78 | HTT (0.53) | ALDH1A1MAPTKMT2AHTTLMNA | |
| SCHEMBL31640059 | 0.78 | HTT (0.53) | ALDH1A1MAPTKMT2AHTTLMNA | |
| SCHEMBL1952190 | 0.77 | ALDH1A1 (0.36) | ALDH1A1MAPTMAPK1KMT2AHTT | |
| SCHEMBL25196247 | 0.77 | POLB (0.41) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL29179880 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTMAPK1KMT2AHTT | |
| SCHEMBL4705323 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTMAPK1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | OXA1L, MRPL21, RPL5 | ALDH1A1 1275/4885MAPT 4653/4885MAPK1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.