SCHEMBL1855073

SCHEMBL1855073

CO[Si](CCCCCCCCCCCOc1ccccc1)(OC)OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.59
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
HDAC9 Q9UKV0 1/20 0.53
HDAC5 Q9UQL6 1/20 0.53
LTA4H P09960 2/20 0.49
DRD2 P14416 2/20 0.49
DRD4 P21917 2/20 0.49
DRD3 P35462 2/20 0.49
HTR1B P28222 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
KCNH2 Q12809 1/20 0.44
HTR1D P28221 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2818268 0.92 KCNA3 (0.58) KCNA3HDAC3HDAC4HDAC1HDAC7
Ammonia Solution, Strong SCHEMBL22654341 0.91 KCNA3 (0.56) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL28980695 0.86 KCNA3 (0.50) KCNA3HDAC3HDAC4HDAC1HDAC7
Boric Acid SCHEMBL28980657 0.86 KCNA3 (0.50) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL12974250 0.83 PPARA (0.61) LTA4HL3MBTL1ALDH1A1
SCHEMBL17476362 0.82 KCNA3 (0.55) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL17476379 0.82 KCNA3 (0.55) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL17476369 0.82 KCNA3 (0.55) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL17476373 0.82 KCNA3 (0.55) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL17476360 0.82 KCNA3 (0.55) KCNA3HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1979363-B1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT ENERGIE ATOMIQUE (FR) 2011-05-25 EP claimed
US-20090029875-A1 Novel Silane Compounds and Use of Same for Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-01-29 US claimed
EP-1979363-A1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-10-15 EP claimed
WO-2007088187-A1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2007-08-09 WO claimed
US-20060188907-A1 Patterning method, substrate for biomolecule immobilization using the patterning method, and biochip employing the substrate SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-08-24 US claimed
US-9657042-B2 Silane compounds and use of same for functionalizing solid supports and immobilizing biological molecules on these supports COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2017-05-23 US disclosed
EP-1979363-B1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT ENERGIE ATOMIQUE (FR) 2011-05-25 EP disclosed
US-20090297868-A1 Method for Forming Self-Assembled Monolayer Film, and Structural Body and Field-Effect Transistor Having Same TOPPAN PRINTING CO., LTD. (JP) 2009-12-03 US disclosed
US-20090029875-A1 Novel Silane Compounds and Use of Same for Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-01-29 US disclosed
EP-1979363-A1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-10-15 EP disclosed
WO-2007088187-A1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2007-08-09 WO disclosed
US-20060188907-A1 Patterning method, substrate for biomolecule immobilization using the patterning method, and biochip employing the substrate SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-08-24 US disclosed
EP-1683571-A1 Patterning method, substrate for biomolecule immobilization using the patterning method, and biochip employing the substrate Samsung Electronics Co., Ltd. (KR) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090029875-A1 Novel Silane Compounds and Use of Same for Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports SELE, ILK, ZYX KCNA3 3496/4885HDAC3 1160/4885HDAC4 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.