Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876766 | 0.83 | MAPT (0.45) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL28760815 | 0.80 | MAPT (0.50) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL7961019 | 0.77 | MAPT (0.47) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL9321186 | 0.71 | ALDH1A1 (0.39) | MAPTALDH1A1ATMMCL1KMT2A | |
| SCHEMBL10339622 | 0.70 | MAPT (0.43) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL29416669 | 0.70 | KMT2A (0.36) | MAPTALDH1A1ATMHPGDKMT2A | |
| SCHEMBL8614888 | 0.70 | MAPT (0.59) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL49783 | 0.69 | MAPT (0.50) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL152956 | 0.69 | EEF2K (0.37) | MAPTALDH1A1HPGDKMT2ATHRB | |
| SCHEMBL5038883 | 0.67 | MAPT (0.50) | MAPTALDH1A1ATMHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482912-B1 | NALTREXONE HYDROCHLORIDE COMPOSITIONS | EURO CELTIQUE SA (LU) | 2011-05-25 | — | — | EP | claimed |
| CN-1308292-C | Succinic acid semi-amides as anti-corrosives agents | CIBA SC HOLDING AG (CH) | 2007-04-04 | — | — | CN | disclosed |
| CN-1681772-A | Succinic acid semi-amides as anti-corrosives agents | CIBA SC HOLDING AG (CH) | 2005-10-12 | — | — | CN | disclosed |
| EP-0769016-B1 | PROCESS FOR PRODUCING LIGHT-COLOURED SURFACTANTS | HENKEL KGAA (DE) | 1998-09-30 | — | — | EP | disclosed |
| US-4371646-A | 2,6-Di-tertiary butyl phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light | ADEKA ARGUS CHEMICAL CO. LTD. (JP) | 1983-02-01 | — | — | US | disclosed |