Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038883 | 0.82 | MAPT (0.50) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL28760815 | 0.82 | MAPT (0.50) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL1855089 | 0.77 | MAPT (0.45) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL7876766 | 0.72 | MAPT (0.45) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL10339622 | 0.72 | MAPT (0.43) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL49783 | 0.70 | MAPT (0.50) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL16682775 | 0.67 | ALDH1A1 (0.31) | MAPTALDH1A1ATMMCL1 | |
| SCHEMBL2576988 | 0.67 | MAPT (0.48) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL853674 | 0.66 | MAPT (0.52) | MAPTALDH1A1ATMHPGDNPSR1 | |
| SCHEMBL359232 | 0.66 | ATM (0.52) | MAPTALDH1A1ATMHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6280893-B1 | CONDUCTIVE SUBSTRATE WITH PHOTOSENSITIVE LAYER, TRANSPORT LAYER AND DICYANOVINYLALKYL SUBSTITUTED CYCLOHEXANONE | SHINDENGEN ELECTRIC MANUFACTURING CO., LTD. (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-0665208-B1 | 4-ALKOXY-2,6-DI-t-BUTYLPHENOL DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5663373-A | ANTIISCHEMIC AGENTS AND ANTIOXIDANTS FORMED IN MULTISTAGE REACTION WITH GRIGNARD REAGENT WITH ALDEHYDE, DISSOLVING, ACIDIFICATION, DEPROTECTION AND CYCLIZATION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5606089-A | ANTIISCHEMIC AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5574178-A | CHEMICAL INTERMEDIATES FOR OXIDATION RESISTANCE AND ANTIISCHEMIC AGENTS FORMED BY MULTISTAGE CYCLIZATION OF ALDEHYDE-ALCOHOL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0665208-A1 | 4-ALKOXY-2,6-DI-t-BUTYLPHENOL DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1995-08-02 | — | — | EP | disclosed |