SCHEMBL18551975

SCHEMBL18551975

NN[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.54
▸ FOLH1 Q04609 2/20 0.39
▸ ITGB3 P05106 1/20 0.39
▸ ITGA2B P08514 1/20 0.39
▸ EPOR P19235 1/20 0.39
▸ CCKAR P32238 4/20 0.38
▸ CCKBR P32239 4/20 0.38
▸ SIRT5 Q9NXA8 1/20 0.37
▸ EPHX2 P34913 2/20 0.37
▸ NOD1 Q9Y239 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18735710 0.92 GLP1R (0.66) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL17401200 0.91 GLP1R (0.67) GLP1RFOLH1CCKARCCKBR
SCHEMBL19786830 0.91 GLP1R (0.67) GLP1RFOLH1CCKARCCKBR
SCHEMBL16948614 0.91 GLP1R (0.61) GLP1RFOLH1ITGB3ITGA2BEPOR
SCHEMBL19307987 0.90 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL16192882 0.90 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL16192883 0.90 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL21099643 0.90 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL21099692 0.90 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL13577551 0.89 GLP1R (0.56) GLP1RFOLH1ITGB3ITGA2BEPOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170051034-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2017-02-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170051034-A1 Novel Glucagon Analogues GLP1R, GIPR, IAPP GLP1R 1/4885FOLH1 303/4885ITGB3 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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