Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848534 | 0.90 | GPR52 (0.49) | GPR52S1PR5S1PR4PTGER1FOLH1 | |
| SCHEMBL1848252 | 0.90 | GPR52 (0.44) | GPR52S1PR5S1PR4S1PR1 | |
| SCHEMBL1854846 | 0.89 | GPR52 (0.44) | GPR52S1PR5S1PR4PTGER1FOLH1 | |
| SCHEMBL3207002 | 0.87 | GPR52 (0.60) | GPR52KLKB1KLK1 | |
| SCHEMBL1855238 | 0.87 | GPR52 (0.47) | GPR52S1PR5S1PR4PTGER1FOLH1 | |
| SCHEMBL1853560 | 0.84 | GPR52 (0.46) | GPR52S1PR5S1PR4 | |
| SCHEMBL1856933 | 0.80 | GPR52 (0.57) | GPR52 | |
| SCHEMBL1856606 | 0.79 | GPR52 (0.48) | GPR52S1PR5S1PR4 | |
| SCHEMBL1848254 | 0.78 | GPR52 (0.47) | GPR52S1PR5S1PR4 | |
| SCHEMBL3206759 | 0.77 | GPR52 (0.63) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |