Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.57 |
| ▸ | FYN | P06241 | 5/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207002 | 0.92 | GPR52 (0.60) | GPR52FYNLIMK1 | |
| SCHEMBL3206759 | 0.88 | GPR52 (0.63) | GPR52FYNLIMK1 | |
| SCHEMBL3213482 | 0.84 | GPR52 (0.69) | GPR52 | |
| SCHEMBL1855236 | 0.80 | GPR52 (0.45) | GPR52 | |
| SCHEMBL3198471 | 0.78 | GPR52 (0.62) | GPR52FYN | |
| SCHEMBL1848252 | 0.77 | GPR52 (0.44) | GPR52 | |
| SCHEMBL3207171 | 0.75 | GPR52 (0.68) | GPR52FYN | |
| SCHEMBL1848534 | 0.75 | GPR52 (0.49) | GPR52 | |
| SCHEMBL13489559 | 0.75 | GPR52 (0.65) | GPR52FYN | |
| SCHEMBL1854846 | 0.75 | GPR52 (0.44) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |