Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13588690 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL18612365 | 0.82 | AURKB (0.48) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL8686061 | 0.82 | PPARA (0.45) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL8684173 | 0.82 | PPARA (0.45) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL4246697 | 0.82 | APP (0.56) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL18580309 | 0.79 | LTA4H (0.45) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL4465201 | 0.78 | CYP1A2 (0.60) | SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21471354 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL18580753 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2002218 | 0.77 | APP (0.47) | SMN1; SMN2NPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340979-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035438-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-03-02 | — | — | WO | disclosed |