Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800618 | 0.85 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL20876039 | 0.84 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL2342820 | 0.80 | PSMB5 (0.40) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL28385360 | 0.78 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL28379902 | 0.78 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL6357414 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL31056287 | 0.77 | SRC (0.47) | ALDH1A1MAPTKDM4ENPSR1GAA | |
| SCHEMBL8649664 | 0.77 | CDK1 (0.46) | ALDH1A1HPGDNPSR1LMNAHTT | |
| SCHEMBL9471487 | 0.77 | TLR8 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL11759112 | 0.77 | ALDH1A3 (0.40) | ALDH1A1ALDH1A3ALDH3A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680395-B1 | NOVEL LIGAND ACTIVATING RAR RECEPTORS USED IN HUMAN MEDICINE AND COSMETICS | GALDERMA RES & DEV (FR) | 2011-05-25 | — | — | EP | disclosed |