Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22593906 | 1.00 | LMNA (0.36) | LMNAALDH1A1TDP1THRBTSHR | |
| Ethylene Glycol SCHEMBL15646244 | 0.96 | LMNA (0.33) | LMNAALDH1A1TDP1THRB | |
| SCHEMBL18391445 | 0.81 | CA1 (0.35) | LMNAALDH1A1TSHRENPEPGABRR1 | |
| SCHEMBL7376386 | 0.81 | CA1 (0.35) | LMNAALDH1A1TSHRENPEPGABRR1 | |
| SCHEMBL29608537 | 0.80 | TSHR (0.33) | TDP1TSHRENPEPGABRR1SLC7A5 | |
| SCHEMBL9611232 | 0.79 | GABRR1 (0.38) | LMNAENPEPGABRR1SLC7A5 | |
| SCHEMBL4751297 | 0.78 | NAALAD2 (0.45) | LMNAALDH1A1TDP1ENPEPGABRR1 | |
| SCHEMBL14795138 | 0.78 | TSHR (0.35) | LMNATDP1TSHRENPEPGABRR1 | |
| SCHEMBL22170188 | 0.77 | CA1 (0.38) | TDP1TSHRGABRR1 | |
| Isobutyramide SCHEMBL6027666 | 0.77 | LMNA (0.50) | LMNAALDH1A1TDP1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340979-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035438-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-03-02 | — | — | WO | disclosed |
| CN-101511328-B | Ultraviolet screening agent for cosmetics and cosmetics using the same | NIPPON CATALYTIC CHEM IND | 2012-11-28 | — | — | CN | disclosed |
| CN-101511328-A | Ultraviolet screening agent for cosmetics and cosmetics using the same | NIPPON CATALYTIC CHEM IND (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-1280324-C | Method for synthesis of hybrid silicone and organic copolymer by controlled freeradical polymerisation | RHONE POULENC CHIMIE (FR) | 2006-10-18 | — | — | CN | disclosed |
| CN-1449417-A | Method for synthesis of hybrid silicone and organic copolymer by controlled freeradical polymerisation | RHONE POULENC CHIMIE (FR) | 2003-10-15 | — | — | CN | disclosed |