Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.37 |
| ▸ | CTSC | P53634 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22559846 | 0.81 | CFD (0.37) | CFDCTSCMEN1KMT2ACD274 | |
| SCHEMBL20378093 | 0.81 | CFD (0.37) | CFDCTSCMEN1KMT2ACD274 | |
| SCHEMBL17024751 | 0.79 | CFD (0.38) | CFDCTSCPTGES | |
| SCHEMBL18576565 | 0.79 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL29545547 | 0.79 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL18555502 | 0.79 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL17053073 | 0.79 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL17023724 | 0.79 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL17031918 | 0.78 | CTSC (0.36) | CFDCTSCMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17023497 | 0.78 | CFD (0.41) | CFDCTSCMEN1KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340982-A1 | COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035408-A1 | COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |