Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.69 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209952 | 0.94 | GPR52 (0.76) | GPR52TAS1R3TAS1R1PIN1NPSR1 | |
| SCHEMBL1851771 | 0.81 | GPR52 (1.00) | GPR52 | |
| SCHEMBL1849964 | 0.80 | GPR52 (0.75) | GPR52ALDH1A1 | |
| SCHEMBL3206803 | 0.79 | GPR52 (0.81) | GPR52ALDH1A1 | |
| SCHEMBL1856609 | 0.77 | GPR52 (0.79) | GPR52ALDH1A1 | |
| SCHEMBL3209943 | 0.77 | GPR52 (0.79) | GPR52ALDH1A1 | |
| SCHEMBL1846506 | 0.77 | GPR52 (0.81) | GPR52ALDH1A1 | |
| SCHEMBL1852519 | 0.75 | GPR52 (0.68) | GPR52ALDH1A1 | |
| SCHEMBL3213465 | 0.74 | GPR52 (0.62) | GPR52CYP1A2CYP2C19 | |
| SCHEMBL1848289 | 0.72 | GPR52 (0.81) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |