Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383681 | 0.86 | HPGD (0.55) | HPGDTYRDAOAKR1B1MAOB | |
| SCHEMBL7544470 | 0.86 | HPGD (0.55) | HPGDTYRDAOAKR1B1MAOB | |
| Ammonia Solution, Strong SCHEMBL6994460 | 0.84 | HPGD (0.53) | HPGDTYRDAOAKR1B1MAOB | |
| SCHEMBL7963724 | 0.83 | HPGD (0.56) | HPGDTYRDAOAKR1B1MAOB | |
| Dimethylamine SCHEMBL5140932 | 0.80 | HPGD (0.49) | HPGDTYRDAOAKR1B1MAOB | |
| SCHEMBL15842660 | 0.79 | HPGD (0.55) | HPGDTYRDAOAKR1B1MAOB | |
| SCHEMBL837687 | 0.79 | HPGD (0.55) | HPGDTYRDAOAKR1B1MAOB | |
| SCHEMBL28312969 | 0.78 | MAOB (0.54) | HPGDTYRDAOAKR1B1MAOB | |
| Benzyl Alcohol SCHEMBL333772 | 0.77 | MAOB (0.48) | HPGDTYRDAOAKR1B1MAOB | |
| SCHEMBL29064589 | 0.76 | HPGD (0.42) | HPGDTYRDAOAKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017032487-A1 | PROTEASOME INHIBITOR COMPRISING A SIGNAL-EMITTING MOIETY | Technische Universität München (DE) | 2017-03-02 | — | — | WO | disclosed |