Dimethylamine

Dimethylamine

SCHEMBL5140932

CNC.O=c1oc2ccccc2cc1C(F)(F)F

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
TYR P14679 1/20 0.49
DAO P14920 1/20 0.49
AKR1B1 P15121 1/20 0.49
POLB P06746 1/20 0.49
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
MAOB P27338 10/20 0.48
MAOA P21397 5/20 0.48
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
CYP1A2 P05177 2/20 0.48
HSD17B10 Q99714 2/20 0.48
LMNA P02545 1/20 0.48
CA12 O43570 3/20 0.47
CA9 Q16790 3/20 0.47
NT5E P21589 1/20 0.47
TSHR P16473 2/20 0.45
CA1 P00915 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7544470 0.93 HPGD (0.55) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL383681 0.93 HPGD (0.55) HPGDSMN1; SMN2TYRDAOAKR1B1
Ammonia Solution, Strong SCHEMBL6994460 0.92 HPGD (0.53) HPGDSMN1; SMN2TYRDAOAKR1B1
Benzyl Alcohol SCHEMBL333772 0.81 MAOB (0.48) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL18554665 0.80 HPGD (0.56) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL837687 0.80 HPGD (0.55) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL24312138 0.77 HPGD (0.51) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL22590858 0.76 RAB9A (0.57) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL15842660 0.76 HPGD (0.55) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL28642209 0.75 MAOB (0.47) MAOBALDH1A1CA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004713-A2 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES Carestream Health, Inc. (US) 2008-12-24 EP disclosed
WO-2007120579-A2 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CARESTREAM HEALTH, INC. (US) 2007-10-25 WO disclosed