Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544470 | 0.98 | HPGD (0.55) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL383681 | 0.98 | HPGD (0.55) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| Dimethylamine SCHEMBL5140932 | 0.92 | HPGD (0.49) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| Benzyl Alcohol SCHEMBL333772 | 0.85 | MAOB (0.48) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL18554665 | 0.84 | HPGD (0.56) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL22590858 | 0.80 | RAB9A (0.57) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL837687 | 0.80 | HPGD (0.55) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL15842660 | 0.80 | HPGD (0.55) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL24312138 | 0.77 | HPGD (0.51) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL15842332 | 0.77 | PGR (0.43) | HPGDMAOBKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555330-B1 | Identifying a compound which modulates apoptosis in transformed cells using a cellular extract from a transformed cell that comprises an apoptotic machinery and a signal capable of activating the apoptotic machinery | COLD SPRING HARBOR LABORATORY | 2003-04-29 | — | — | US | disclosed |
| EP-1268414-A1 | CERAMIDE DERIVATIVES AND METHOD OF USE | The Liposome Company, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1269193-A2 | A LYSOSOMAL PEPSTATIN-INSENSITIVE PROTEINASE AS BIOMARKER FOR BREAST CANCER | Research Foundation for Mental Hygiene, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072701-A1 | CERAMIDE DERIVATIVES AND METHOD OF USE | THE LIPOSOME COMPANY, INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001069260-A2 | A LYSOSOMAL PEPSTATIN-INSENSITIVE PROTEINASE AS A NOVEL BIOMARKER FOR DETECTING AND DIAGNOSING BREAST CANCER | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (US) | 2001-09-20 | — | — | WO | disclosed |
| US-20010006793-A1 | MODULATORS OF EUKARYOTIC CASPASES | THOMAS JEFFERSON UNIVERSITY | 2001-07-05 | — | — | US | disclosed |