Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | DDT | P30046 | 1/20 | 0.42 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848790 | 0.89 | KMO (0.43) | KMODDTEIF4EBP1FNTAFNTB | |
| SCHEMBL1853489 | 0.74 | NPC1 (0.46) | — | |
| SCHEMBL16734982 | 0.71 | PIK3CG (0.62) | — | |
| SCHEMBL3212711 | 0.68 | GPR52 (0.55) | EIF4EBP1PTGER1CYP3A4CYP2C9 | |
| SCHEMBL1855057 | 0.68 | GPR52 (0.54) | KMOEIF4EBP1PTGER1FOLH1MAOA | |
| SCHEMBL29725579 | 0.67 | KMO (0.74) | KMODDTCHEK1AXLKEAP1 | |
| SCHEMBL29911642 | 0.67 | KMO (0.74) | KMODDTCHEK1AXLKEAP1 | |
| SCHEMBL382724 | 0.67 | KMO (0.70) | KMODDTFNTAFNTBPTGER1 | |
| SCHEMBL16749639 | 0.67 | KMO (0.69) | KMODDTFOLH1KEAP1CYP2C9 | |
| SCHEMBL29386545 | 0.67 | KMO (0.69) | KMODDTFOLH1KEAP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |