Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | TOP1 | P11387 | 4/20 | 0.32 |
| ▸ | TOP2A | P11388 | 9/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523724 | 0.90 | ALDH1A1 (0.56) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL29821427 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL8509346 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL3198924 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL13483604 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL74553 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL1652843 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL29368438 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL21416358 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 | |
| Sitafloxacin Anhydrous SCHEMBL2784482 | 0.89 | ALDH1A1 (0.59) | POLBALDH1A1CHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408034-B2 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | BAYER INNOVATION GMBH (DE) | 2011-05-25 | — | — | EP | claimed |
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | claimed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | claimed |
| EP-1408034-B2 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | BAYER INNOVATION GMBH (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | disclosed |
| EP-1244434-A2 | USE OF CHEMOTHERAPEUTIC AGENTS | Schulz, Hans-Herrmann (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001045679-A2 | USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT | SCHULZ HANS HERRMANN (DE) | 2001-06-28 | — | — | WO | disclosed |