Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18555403 | 0.84 | PRMT5 (0.44) | PRMT5WDR77MEN1KMT2ACCR2 | |
| SCHEMBL18555694 | 0.81 | PRMT5 (0.46) | PRMT5WDR77MEN1KMT2ACCR2 | |
| SCHEMBL18555749 | 0.79 | FFAR1 (0.45) | FFAR1ERN1PTGDR2 | |
| SCHEMBL11257792 | 0.78 | MEN1 (0.64) | GABRA5MEN1KMT2ATBXA2RMAPT | |
| SCHEMBL10254276 | 0.77 | MAPT (0.44) | PIK3CDGABRA5GABRA1MEN1KMT2A | |
| SCHEMBL18555697 | 0.76 | PTGS2 (0.52) | MEN1KMT2ACCR2 | |
| SCHEMBL18180375 | 0.71 | APEX1 (0.57) | — | |
| SCHEMBL11262469 | 0.71 | TSHR (0.63) | KMT2AMAPTRXFP1 | |
| SCHEMBL18555395 | 0.70 | FFAR1 (0.46) | FFAR1ERN1PTGDR2 | |
| SCHEMBL703609 | 0.69 | APP (0.52) | FFAR1KMT2AERN1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035415-A1 | ALKYNE COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |