Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 8/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18555490 | 1.00 | PTGER3 (0.52) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL17341956 | 0.89 | PTGER4 (0.43) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL8746633 | 0.87 | CA1 (0.57) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL30560916 | 0.80 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL690917 | 0.80 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL691503 | 0.80 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL17345581 | 0.80 | PAM (0.47) | PTGER3PTGER2PTGER4PTGER1KDM4E | |
| SCHEMBL78555 | 0.80 | CA1 (0.62) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL78556 | 0.80 | CA1 (0.62) | PTGER3PTGER2PTGER4PTGER1CA1 | |
| SCHEMBL29386378 | 0.80 | CA1 (0.62) | PTGER3PTGER2PTGER4PTGER1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035288-A1 | COMPOSITION AND METHOD FOR PREVENTION, MITIGATION OR TREATMENT OF AN ENTEROPATHOGENIC BACTERIAL INFECTION | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-03-02 | — | — | WO | disclosed |