SCHEMBL30560916

SCHEMBL30560916

Cc1cccc(C=CC(=O)O)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
NFKB1 P19838 1/20 0.53
CA4 P22748 1/20 0.53
PTGER3 P43115 8/20 0.52
PTGER2 P43116 8/20 0.52
PTGER4 P35408 7/20 0.52
PTGER1 P34995 4/20 0.52
KDM4E B2RXH2 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
HDAC3 O15379 1/20 0.45
TNKS O95271 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL690917 1.00 CA1 (0.53) CA1CA2NFKB1CA4PTGER3
SCHEMBL691503 1.00 CA1 (0.53) CA1CA2NFKB1CA4PTGER3
SCHEMBL10589353 0.85 NFKB1 (0.69) CA1CA2NFKB1CA4PTGER3
SCHEMBL3811894 0.84 PTGER3 (0.50) CA1CA2NFKB1CA4PTGER3
SCHEMBL3811892 0.84 PTGER3 (0.50) CA1CA2NFKB1CA4PTGER3
SCHEMBL78556 0.84 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL2425317 0.84 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL78555 0.84 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL29386378 0.84 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL11830587 0.83 PTGER3 (0.71) CA1CA2NFKB1CA4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN claimed
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN disclosed
CN-116768792-B Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2024-10-18 CN disclosed
CN-116768792-A Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2023-09-19 CN disclosed