SCHEMBL1855604

SCHEMBL1855604

N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)OCc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.73
LAP3 P28838 1/20 0.73
PPARG P37231 3/20 0.58
PPARA Q07869 3/20 0.58
FFAR1 O14842 1/20 0.57
FFAR4 Q5NUL3 1/20 0.57
MAOB P27338 2/20 0.55
PARP10 Q53GL7 1/20 0.55
LNPEP Q9UIQ6 1/20 0.55
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
ALOX5 P09917 1/20 0.52
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
PPARD Q03181 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561218 1.00 LTA4H (0.73) LTA4HLAP3PPARGPPARAFFAR1
SCHEMBL8413771 1.00 LTA4H (0.73) LTA4HLAP3PPARGPPARAFFAR1
Hydrochloric Acid SCHEMBL6271718 0.99 LTA4H (0.71) LTA4HLAP3PPARGPPARAFFAR1
Hydrochloric Acid SCHEMBL10922580 0.99 LTA4H (0.71) LTA4HLAP3PPARGPPARAFFAR1
SCHEMBL17738622 0.93 LTA4H (0.64) LTA4HLAP3PPARGPPARAFFAR1
SCHEMBL18025356 0.93 LTA4H (0.64) LTA4HLAP3PPARGPPARAFFAR1
SCHEMBL16607620 0.93 LTA4H (0.67) LTA4HLAP3PPARGPPARAFFAR1
SCHEMBL6713179 0.90 LMNA (0.64) LTA4HLAP3PPARGPPARAFFAR1
SCHEMBL9731697 0.90 LTA4H (0.61) LTA4HLAP3PPARGPPARAMAOB
SCHEMBL9731692 0.90 LTA4H (0.61) LTA4HLAP3PPARGPPARAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191338-A1 LEVODOPA-PRODRUGS AND CARBIDOPA-PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE MITSUBISHI TANABE PHARMA CORPORATION (JP) 2022-09-15 WO disclosed
EP-1697400-B1 BIPHENYL-SUBSTITUTED ANTIBACTERIAL MACROCYCLES AICURIS GMBH & CO KG (DE) 2011-05-25 EP disclosed
US-20040062773-A1 Compositions for the delivery of antigens EMISPHERE TECHNOLOGIES INC. 2004-04-01 US disclosed
EP-0784469-B1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 2004-03-24 EP disclosed
US-6610329-B2 Using acylated amino acid as carrier EMISPHERE TECHNOLOGIES INC. 2003-08-26 US disclosed
US-20020001591-A1 Compositions for the delivery of antigens EMISPHERE TECHNOLOGIES, INC. 2002-01-03 US disclosed
US-5958457-A MIXTURES OF ANTIGENS WITH ADJUVANTS AND ACYLATED AMINO ACIDS OR SALTS, POLYMERS OR SULFONATED AMINO ACIDS EMISPHERE TECHNOLOGIES, INC. (US) 1999-09-28 US disclosed
EP-0784469-A4 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 1999-03-24 EP disclosed
EP-0784469-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS Emisphere Technologies, Inc. (US) 1997-07-23 EP disclosed
WO-1996012474-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECHNOLOGIES, INC. (US) 1996-05-02 WO disclosed
EP-0226158-B1 PEPTIDES CORRELATED TO LYSOZYME S P A SOCIETA' PRODOTTI ANTIBIOTICI S.p.a. (IT) 1992-06-10 EP disclosed
US-4784988-A OLIGO AND POLYPEPTIDES, ANALGESICS, VIRICIDES SPA SOCIETA' PRODOTTI ANTIBIOTICI S.P.A. (IT) 1988-11-15 US disclosed
EP-0226158-A2 Peptides correlated to lysozyme S P A SOCIETA' PRODOTTI ANTIBIOTICI S.p.a. (IT) 1987-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020001591-A1 Compositions for the delivery of antigens CD47, CD74, LY96 LTA4H 1415/4885LAP3 286/4885PPARG 2770/4885
US-20040062773-A1 Compositions for the delivery of antigens CD47, CD74, LY96 LTA4H 1415/4885LAP3 286/4885PPARG 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.