SCHEMBL18556753

SCHEMBL18556753

CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 12/20 0.64
▸ NPBWR1 P48145 4/20 0.64
▸ CCKBR P32239 2/20 0.61
▸ MC4R P32245 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18556710 0.97 IL23R (0.63) IL23RNPBWR1CCKBRMC4R
SCHEMBL18556748 0.97 CCKBR (0.64) IL23RNPBWR1CCKBRMC4R
SCHEMBL12094775 0.95 IL23R (0.59) IL23RNPBWR1CCKBRMC4R
SCHEMBL12094766 0.94 IL23R (0.62) IL23RNPBWR1MC4R
SCHEMBL12094739 0.93 MC4R (0.59) IL23RNPBWR1CCKBRMC4R
SCHEMBL12094803 0.93 MC4R (0.62) IL23RCCKBRMC4R
SCHEMBL12094761 0.93 MC4R (0.62) IL23RCCKBRMC4R
SCHEMBL12094778 0.93 MC4R (0.62) IL23RCCKBRMC4R
SCHEMBL12094740 0.93 MC4R (0.62) IL23RCCKBRMC4R
SCHEMBL12094763 0.93 MC4R (0.62) IL23RCCKBRMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2017-05-25 — — US disclosed
US-9580466-B2 Melanocortin-1 receptor-specific linear peptides PALATIN TECHNOLOGIES, INC. (US) 2017-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC5R, MC3R IL23R 466/4885NPBWR1 69/4885CCKBR 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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