Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767013 | 0.84 | KMT2A (0.53) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL6937970 | 0.82 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL27302811 | 0.79 | TSHR (0.47) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL20766727 | 0.77 | KMT2A (0.42) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL21705619 | 0.76 | KMT2A (0.39) | HTTKMT2ASMN1; SMN2TDP1KDM1A | |
| SCHEMBL1543564 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM2CHRM4CHRM3ULK1 | |
| SCHEMBL28410100 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM2CHRM4CHRM3ULK1 | |
| SCHEMBL14166088 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM2CHRM4CHRM3ULK1 | |
| SCHEMBL1543565 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM2CHRM4CHRM3ULK1 | |
| SCHEMBL2983518 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM2CHRM4CHRM3ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579390-B2 | Compounds and methods for producing a conjugate | REDWOOD BIOSCIENCE, INC. (US) | 2017-02-28 | — | — | US | disclosed |