Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767013 | 0.86 | KMT2A (0.53) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL18556770 | 0.82 | HTT (0.40) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL27302811 | 0.80 | TSHR (0.47) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL20766727 | 0.78 | KMT2A (0.42) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL18733388 | 0.77 | SMN1; SMN2 (0.43) | HTTKMT2ASMN1; SMN2TDP1CHRM2 | |
| SCHEMBL14725889 | 0.77 | SMN1; SMN2 (0.43) | HTTKMT2ASMN1; SMN2TDP1CHRM2 | |
| SCHEMBL16671330 | 0.76 | HTT (0.32) | HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL10087740 | 0.72 | TAS1R3 (0.46) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL25128746 | 0.72 | KMT2A (0.37) | HTTKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL17968590 | 0.71 | POLB (0.42) | HTTKMT2ASMN1; SMN2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |