Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SRSF6 | Q13247 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557636 | 0.93 | ADRB2 (0.38) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL18016240 | 0.87 | ADRB2 (0.40) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL18946765 | 0.81 | ADRB2 (0.45) | ADRB2ADRB1 | |
| SCHEMBL18023602 | 0.80 | ADRB2 (0.45) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL18016238 | 0.79 | ADRB2 (0.39) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL17978658 | 0.78 | ADRB2 (0.42) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL18946387 | 0.75 | ADRB2 (0.48) | ADRB2ADRB1 | |
| SCHEMBL17978747 | 0.72 | ADRB2 (0.41) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL28423956 | 0.72 | ADRB2 (0.41) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL28424321 | 0.72 | ADRB2 (0.41) | ADRB2ADRB1DRD3SLC6A2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579314-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-02-28 | — | — | US | disclosed |