Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741549 | 0.90 | CHRM3 (0.66) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL16789092 | 0.85 | CHRM3 (0.51) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL16791256 | 0.81 | CHRM3 (0.83) | CHRM3 | |
| SCHEMBL14240957 | 0.81 | CHRM3 (0.83) | CHRM3 | |
| SCHEMBL9329438 | 0.80 | CHRM3 (0.54) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL19894876 | 0.79 | CHRM3 (0.51) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294695 | 0.79 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294694 | 0.79 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294779 | 0.79 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294693 | 0.79 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579314-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-02-28 | — | — | US | disclosed |