Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741549 | 0.88 | CHRM3 (0.66) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL18557643 | 0.80 | CHRM3 (0.56) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL19049351 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294778 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17301741 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294779 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294695 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294694 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294693 | 0.77 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL2482949 | 0.76 | CHRM3 (0.63) | CHRM3CHRNA7BCHEACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424021-B1 | Antimuscarinic bronchodilators | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| US-5171744-A | Antimuscarinic bronchodilators | PFIZER INC. (US) | 1992-12-15 | — | — | US | disclosed |
| CN-1051041-A | Antimuscainic bronchodilators | PFIZER (US) | 1991-05-01 | — | — | CN | disclosed |
| EP-0424021-A1 | Antimuscarinic bronchodilators | Pfizer Limited (GB) | 1991-04-24 | — | — | EP | disclosed |