Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 14/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18017290 | 0.87 | ADRB2 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18557745 | 0.84 | ADRB2 (0.57) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL18813850 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL24404454 | 0.81 | ADRB2 (0.53) | ADRB2CHRM3ADRB1ADRB3CHRM2 | |
| SCHEMBL18557747 | 0.80 | ADRB2 (0.57) | ADRB2CHRM3ADRB1ADRB3CHRM2 | |
| SCHEMBL21568647 | 0.80 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568646 | 0.80 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL24404436 | 0.80 | ADRB2 (0.55) | ADRB2CHRM3ADRB1ADRB3CHRM2 | |
| SCHEMBL24404497 | 0.80 | ADRB2 (0.56) | ADRB2CHRM3ADRB1 | |
| SCHEMBL17074683 | 0.79 | ADRB2 (0.71) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579314-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-02-28 | — | — | US | disclosed |