Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18813850 | 0.94 | ADRB2 (0.56) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL18017290 | 0.86 | ADRB2 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL21568646 | 0.83 | ADRB2 (0.61) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL21568647 | 0.83 | ADRB2 (0.61) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL18557690 | 0.81 | ADRB2 (0.58) | ADRB2ADRB1ADRB3CHRM3CHRM2 | |
| SCHEMBL17978762 | 0.79 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL17978760 | 0.79 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL17978803 | 0.79 | ADRB2 (0.59) | ADRB2CHRM3 | |
| SCHEMBL17978826 | 0.79 | ADRB2 (0.59) | ADRB2CHRM3 | |
| SCHEMBL18557747 | 0.78 | ADRB2 (0.57) | ADRB2ADRB1ADRB3CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256464-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2022-05-11 | — | — | EP | disclosed |