Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978913 | 0.82 | GPR119 (0.47) | GPR119SLC2A1YAP1EPHX2 | |
| SCHEMBL31457748 | 0.82 | GPR119 (0.53) | GPR119SLC2A1YAP1 | |
| SCHEMBL2766618 | 0.81 | GPR119 (0.58) | GPR119SLC2A1YAP1SGMS1SGMS2 | |
| SCHEMBL2768171 | 0.79 | GPR119 (0.60) | GPR119SLC2A1YAP1SGMS1SGMS2 | |
| SCHEMBL22839895 | 0.79 | GPR119 (0.47) | GPR119SLC2A1YAP1 | |
| SCHEMBL3362056 | 0.78 | KDM4E (0.57) | GPR119YAP1 | |
| SCHEMBL13888078 | 0.77 | GPR119 (0.62) | GPR119SLC2A1YAP1SGMS1SGMS2 | |
| SCHEMBL13865088 | 0.76 | GPR119 (0.61) | GPR119SLC2A1YAP1SGMS1SGMS2 | |
| SCHEMBL17078825 | 0.75 | SLC2A1 (0.61) | GPR119SLC2A1YAP1 | |
| SCHEMBL3360747 | 0.75 | KDM4E (0.56) | GPR119YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579314-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-02-28 | — | — | US | disclosed |