Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | YAP1 | P46937 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362056 | 0.88 | KDM4E (0.57) | GPR119KDM4EPKMTGFBR1YAP1 | |
| SCHEMBL391151 | 0.81 | GPR119 (0.52) | GPR119KDM4EPKMSLC2A1 | |
| SCHEMBL30812262 | 0.81 | GPR119 (0.51) | GPR119KDM4EPKMTGFBR1YAP1 | |
| SCHEMBL13097087 | 0.81 | SLC2A1 (0.57) | GPR119KDM4EPKMTGFBR1SLC2A1 | |
| SCHEMBL7160444 | 0.79 | KDM1A (0.52) | GPR119KDM1A | |
| SCHEMBL18557723 | 0.79 | GPR119 (0.49) | GPR119YAP1SLC2A1 | |
| SCHEMBL27379752 | 0.79 | GPR119 (0.50) | GPR119KDM4EPKMTGFBR1STS | |
| SCHEMBL3360747 | 0.78 | KDM4E (0.56) | GPR119KDM4EPKMYAP1STS | |
| SCHEMBL29631500 | 0.78 | CHRM3 (0.54) | GPR119KDM4EPKMTGFBR1YAP1 | |
| SCHEMBL17978800 | 0.78 | CHRM3 (0.54) | GPR119KDM4EPKMTGFBR1YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |