Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213412 | 0.93 | GPR52 (0.73) | GPR52MRGPRX4MEN1KMT2A | |
| SCHEMBL1856392 | 0.91 | GPR52 (0.55) | GPR52MRGPRX4MEN1MAPTKMT2A | |
| SCHEMBL1849132 | 0.91 | GPR52 (0.49) | GPR52LMNAMEN1MAPTKMT2A | |
| SCHEMBL1856519 | 0.90 | GPR52 (0.65) | GPR52MRGPRX4ALDH1A1POLB | |
| SCHEMBL1847725 | 0.88 | GPR52 (0.70) | GPR52MRGPRX4 | |
| SCHEMBL3206568 | 0.85 | GPR52 (0.62) | GPR52MRGPRX4MEN1KMT2A | |
| SCHEMBL3210910 | 0.84 | GPR52 (0.71) | GPR52MRGPRX4 | |
| SCHEMBL1850978 | 0.83 | GPR52 (0.49) | GPR52LMNAMEN1MAPTKMT2A | |
| SCHEMBL1848431 | 0.82 | GPR52 (0.42) | GPR52LMNAMEN1MAPTKMT2A | |
| SCHEMBL1855487 | 0.81 | GPR52 (0.55) | GPR52MRGPRX4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |