Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 5/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.42 |
| ▸ | STK25 | O00506 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558588 | 0.91 | RAB9A (0.43) | STK25RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9920918 | 0.90 | CCNA2 (0.51) | CCNA2CDK2CCNA1STK25MEN1 | |
| SCHEMBL18558140 | 0.90 | STK25 (0.43) | STK25RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9921027 | 0.90 | CCNA2 (0.43) | CCNA2CDK2CCNA1STK25RAB9A | |
| SCHEMBL9921043 | 0.90 | STK25 (0.43) | CCNA2CDK2CCNA1STK25MEN1 | |
| SCHEMBL9920997 | 0.88 | STK25 (0.39) | CCNA2CDK2CCNA1STK25EPHX2 | |
| SCHEMBL9920897 | 0.87 | STK25 (0.39) | CCNA2CDK2CCNA1STK25RAB9A | |
| SCHEMBL9920808 | 0.86 | NPC1 (0.42) | CCNA2CDK2CCNA1STK25RAB9A | |
| SCHEMBL18558471 | 0.84 | STK25 (0.40) | STK25RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9920841 | 0.82 | CCNA2 (0.41) | CCNA2CDK2CCNA1STK25RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |