Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | STK25 | O00506 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921043 | 0.91 | STK25 (0.43) | STK25ACKR3HDAC4MEN1KMT2A | |
| SCHEMBL9921027 | 0.91 | CCNA2 (0.43) | RAB9ANPC1STK25EPHX1TACR2 | |
| SCHEMBL18558140 | 0.91 | STK25 (0.43) | RAB9ANPC1STK25EPHX1CRHR1 | |
| SCHEMBL18558261 | 0.91 | CCNA2 (0.42) | RAB9ANPC1STK25EPHX1CRHR1 | |
| SCHEMBL9920808 | 0.89 | NPC1 (0.42) | RAB9ANPC1STK25ACKR3CRHR1 | |
| SCHEMBL9920997 | 0.89 | STK25 (0.39) | STK25IDO1CRHR1HDAC4 | |
| SCHEMBL9920897 | 0.88 | STK25 (0.39) | RAB9ANPC1STK25EPHX1IDO1 | |
| SCHEMBL18558471 | 0.88 | STK25 (0.40) | RAB9ANPC1STK25IDO1CRHR1 | |
| SCHEMBL18558518 | 0.85 | RAB9A (0.54) | RAB9ANPC1EPHX1TDP1CRHR1 | |
| SCHEMBL9920918 | 0.85 | CCNA2 (0.51) | STK25ACKR3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |