Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10017405 | 0.79 | PRMT6 (0.65) | ADRA1DPRMT6ALDH1A1LMNATHRB | |
| SCHEMBL18719410 | 0.70 | PRMT6 (0.54) | ADRA1DPRMT6ALDH1A1LMNATHRB | |
| SCHEMBL20461843 | 0.70 | PRMT6 (0.48) | ADRA1DPRMT6ALDH1A1THRBTP53 | |
| SCHEMBL26542057 | 0.68 | PRMT6 (0.52) | ADRA1DPRMT6ALDH1A1THRBTP53 | |
| SCHEMBL1681056 | 0.68 | PRMT6 (0.52) | ADRA1DPRMT6ALDH1A1THRBTP53 | |
| SCHEMBL1681003 | 0.68 | PRMT6 (0.52) | ADRA1DPRMT6ALDH1A1THRBTP53 | |
| SCHEMBL14038643 | 0.66 | — | — | |
| SCHEMBL19646466 | 0.66 | — | — | |
| SCHEMBL14864810 | 0.66 | ADRA1D (0.46) | ADRA1DPRMT6ALDH1A1LMNATHRB | |
| SCHEMBL21386931 | 0.65 | PRMT6 (0.48) | ADRA1DPRMT6ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580438-B2 | Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and CNS disorders | 4SC DISCOVERY GMBH (DE) | 2017-02-28 | — | — | US | disclosed |