Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310811 | 0.88 | TSHR (0.37) | LMNAMAPTTSHRALOX15CA1 | |
| SCHEMBL13672288 | 0.83 | CA1 (0.44) | PRKCAPRKCDCTSKCA1CA2 | |
| SCHEMBL13672284 | 0.79 | CHRM1 (0.43) | PRKCAPRKCDTSHRCA2CHRM1 | |
| SCHEMBL10184196 | 0.76 | MAPT (0.39) | LMNAMAPTTSHRALOX15 | |
| SCHEMBL28061921 | 0.76 | PRKCA (0.41) | PRKCAPRKCDMAPTTSHRCTSK | |
| SCHEMBL26020478 | 0.74 | PRKCA (0.35) | PRKCAPRKCDLMNAALOX15 | |
| SCHEMBL15472457 | 0.73 | TSHR (0.46) | LMNATSHRCA1CA2ADRA1A | |
| SCHEMBL10309264 | 0.73 | TSHR (0.32) | PRKCAPRKCDTSHR | |
| SCHEMBL15472458 | 0.73 | TSHR (0.46) | LMNATSHRCA1CA2ADRA1A | |
| SCHEMBL14038946 | 0.73 | TSHR (0.46) | LMNATSHRCA1CA2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579332-B2 | Phosphonate analogs of HIV inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2017-02-28 | — | — | US | disclosed |