Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310811 | 0.83 | TSHR (0.37) | MAPTTSHRLMNAALOX15HCAR2 | |
| SCHEMBL19112515 | 0.82 | MAPT (0.36) | MAPT | |
| SCHEMBL13976627 | 0.82 | MAPT (0.36) | MAPT | |
| SCHEMBL15246047 | 0.80 | MAPT (0.36) | MAPT | |
| SCHEMBL18175329 | 0.80 | ALDH1A1 (0.40) | MAPTTSHRLMNAALOX15 | |
| SCHEMBL15472457 | 0.79 | TSHR (0.46) | TSHRLMNAHCAR2 | |
| SCHEMBL15472458 | 0.79 | TSHR (0.46) | TSHRLMNAHCAR2 | |
| SCHEMBL14038946 | 0.79 | TSHR (0.46) | TSHRLMNAHCAR2 | |
| SCHEMBL18558703 | 0.76 | PRKCA (0.37) | MAPTTSHRLMNAALOX15 | |
| SCHEMBL14771616 | 0.75 | CA2 (0.35) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | PNP, NSUN2, CDA | MAPT 4506/4885TSHR 1948/4885LMNA 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.