Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559231 | 0.86 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL18559322 | 0.81 | ALDH1A1 (0.80) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL18559346 | 0.81 | ALDH1A1 (0.80) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL4211196 | 0.81 | ALDH1A1 (0.90) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL11888617 | 0.73 | LMNA (0.67) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL4205750 | 0.72 | HTT (0.79) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL4206108 | 0.71 | HTT (0.80) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL18559230 | 0.71 | ALDH1A1 (0.82) | ALDH1A1MAPTHPGDMAPK1LMNA | |
| SCHEMBL4209292 | 0.70 | HTT (0.89) | ALDH1A1GAAMAPTHTTHPGD | |
| SCHEMBL4215730 | 0.69 | ALDH1A1 (0.71) | ALDH1A1GAAMAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |