Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754871 | 0.86 | ROCK2 (0.55) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL22079235 | 0.86 | ROCK2 (0.55) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL263567 | 0.86 | ROCK2 (0.55) | MAPTKDM4EMEN1KMT2APKM | |
| SCHEMBL84390 | 0.85 | MAPT (0.60) | MAPTKDM4EMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL28598924 | 0.84 | ROCK2 (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1210017 | 0.84 | ROCK2 (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1210209 | 0.84 | ROCK2 (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28598925 | 0.84 | ROCK2 (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29915566 | 0.84 | ROCK2 (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21510145 | 0.82 | MAPT (0.50) | MAPTKDM4EMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580427-B2 | Kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-28 | — | — | US | disclosed |