Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24415179 | 0.95 | GLP1R (0.47) | GLP1RNOD1EPOREPHX2ITGB3 | |
| SCHEMBL20146951 | 0.95 | GLP1R (0.52) | GLP1RNOD1EPORTLR2 | |
| SCHEMBL20652822 | 0.91 | GLP1R (0.54) | GLP1RNOD1EPOREPHX2ITGB3 | |
| SCHEMBL20652766 | 0.91 | GLP1R (0.54) | GLP1RNOD1EPOREPHX2ITGB3 | |
| SCHEMBL20653022 | 0.91 | GLP1R (0.54) | GLP1RNOD1EPOREPHX2ITGB3 | |
| SCHEMBL20652648 | 0.91 | GLP1R (0.54) | GLP1RNOD1EPOREPHX2ITGB3 | |
| SCHEMBL24538414 | 0.90 | GLP1R (0.65) | GLP1RNOD1FOLH1 | |
| SCHEMBL23253773 | 0.90 | GLP1R (0.65) | GLP1RNOD1FOLH1 | |
| SCHEMBL23253769 | 0.90 | GLP1R (0.65) | GLP1RNOD1FOLH1 | |
| SCHEMBL20652739 | 0.90 | GLP1R (0.65) | GLP1RNOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513141-B1 | GLP-1 ANALOGUES AND DERIVATIVES | NOVO NORDISK AS (DK) | 2017-03-01 | — | — | EP | disclosed |