SCHEMBL20652766

SCHEMBL20652766

NC(CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.54
▸ NOD1 Q9Y239 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.41
▸ OTC P00480 1/20 0.40
▸ EPOR P19235 1/20 0.40
▸ BHMT Q93088 2/20 0.39
▸ FOLH1 Q04609 2/20 0.39
▸ EPHX2 P34913 3/20 0.39
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20652822 1.00 GLP1R (0.54) GLP1RNOD1TDP1OTCEPOR
SCHEMBL20653022 1.00 GLP1R (0.54) GLP1RNOD1TDP1OTCEPOR
SCHEMBL20652648 1.00 GLP1R (0.54) GLP1RNOD1TDP1OTCEPOR
SCHEMBL19034938 0.99 GLP1R (0.55) GLP1RNOD1TDP1OTCEPOR
SCHEMBL19049678 0.99 GLP1R (0.55) GLP1RNOD1TDP1OTCEPOR
SCHEMBL19034958 0.99 GLP1R (0.55) GLP1RNOD1TDP1OTCEPOR
SCHEMBL19034928 0.99 GLP1R (0.55) GLP1RNOD1TDP1OTCEPOR
SCHEMBL11920426 0.92 GLP1R (0.48) GLP1RNOD1TDP1OTCEPOR
SCHEMBL23839871 0.91 GLP1R (0.52) GLP1RNOD1EPORFOLH1EPHX2
SCHEMBL18560331 0.91 GLP1R (0.50) GLP1RNOD1EPORFOLH1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10822385-B2 EGF(A) analogues with fatty acid substituents NOVO NORDISK A/S (DK) 2020-11-03 — — US disclosed
US-20190016768-A1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS NOVO NORDISK A/S (DK) 2019-01-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190016768-A1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS EGFR, LDLR, FFAR2 GLP1R 39/4885NOD1 4794/4885TDP1 4440/4885
US-10822385-B2 EGF(A) analogues with fatty acid substituents EGFR, LDLR, FFAR2 GLP1R 39/4885NOD1 4794/4885TDP1 4440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback