SCHEMBL18560744

SCHEMBL18560744

c1ccc(-c2ccc(-c3cccc(-c4cccc(-n5c6ccc(-c7ccc8oc9ccccc9c8c7)cc6c6cc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)ccc65)n4)c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
PLA2G10 O15496 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
PRKDC P78527 1/20 0.33
PTGER4 P35408 1/20 0.32
CHEK2 O96017 1/20 0.32
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
PTPRF P10586 5/20 0.32
PTPN2 P17706 5/20 0.32
PTPN1 P18031 5/20 0.32
TSPO P30536 1/20 0.31
HPSE Q9Y251 1/20 0.31
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18560779 0.97 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL18158874 0.97 KDM4E (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL16452315 0.94 KDM4E (0.35) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL16452066 0.94 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL16452251 0.92 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL16452299 0.92 KDM4E (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL14770691 0.92 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL14770611 0.92 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL12455122 0.92 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10KDM4EPRKDC
SCHEMBL14770599 0.92 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10L3MBTL1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062730-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-03-02 US disclosed
US-20170062730-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-03-02 US disclosed