Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 5/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20706680 | 0.93 | CASP3 (0.38) | PLA2G2APLA2G4APLA2G10PTPRFPTPN2 | |
| SCHEMBL18560744 | 0.92 | PLA2G2A (0.38) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL24813199 | 0.91 | PLA2G2A (0.39) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL14770611 | 0.91 | PLA2G2A (0.36) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL16452328 | 0.91 | PLA2G2A (0.36) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL14770691 | 0.91 | PLA2G2A (0.36) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL12455122 | 0.91 | PLA2G2A (0.40) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL19849260 | 0.90 | PLA2G2A (0.37) | PLA2G2APLA2G4APLA2G10PRKDCPGR | |
| SCHEMBL16674255 | 0.90 | PLA2G2A (0.37) | PLA2G2APLA2G4APLA2G10PTPRFPTPN2 | |
| SCHEMBL18560779 | 0.89 | PLA2G2A (0.36) | PLA2G2APLA2G4APLA2G10PRKDCPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | PLA2G2A 4744/4885PLA2G4A 4639/4885PLA2G10 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.