Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857447 | 0.91 | STAT5B (0.43) | STAT5BHSD11B1PTGESSMN1; SMN2PTGER2 | |
| SCHEMBL3635463 | 0.85 | STAT5B (0.44) | STAT5BHSD11B1PTGESKCNH2TAS2R14 | |
| SCHEMBL1855707 | 0.84 | F2 (0.40) | PTGESSMN1; SMN2PTGDR2KMT2ALMNA | |
| SCHEMBL1858017 | 0.83 | PTGDR2 (0.41) | HSD11B1SMN1; SMN2PTGDR2KMT2AMEN1 | |
| SCHEMBL1857129 | 0.82 | STAT5B (0.46) | STAT5BHSD11B1PTGESSMN1; SMN2AKT1 | |
| SCHEMBL1856318 | 0.80 | PTGDR2 (0.36) | HSD11B1PTGESSMN1; SMN2PTGER2TAS2R14 | |
| SCHEMBL1860642 | 0.78 | CA12 (0.38) | STAT5BPTGDR2ALDH1A1LMNAPOLB | |
| SCHEMBL1860465 | 0.76 | PTGDR2 (0.38) | PTGDR2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4015477 | 0.76 | PTGDR2 (0.45) | HSD11B1SMN1; SMN2PTGER2PTGDR2KMT2A | |
| SCHEMBL1856322 | 0.76 | PTGDR2 (0.37) | PTGER2PTGDR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2011-05-05 | — | — | US | disclosed |
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | AKR1C3, TPD52L2, HCCS | STAT5B 4233/4885HSD11B1 826/4885PTGES 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.