Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011688 | 0.88 | PTGDR2 (0.43) | PTGDR2HSD11B1HAO1MEN1KMT2A | |
| SCHEMBL4009251 | 0.83 | HSD11B1 (0.43) | HSD11B1CA12CA2CA9SMN1; SMN2 | |
| SCHEMBL1858017 | 0.83 | PTGDR2 (0.41) | PTGDR2HSD11B1HAO1MEN1KMT2A | |
| SCHEMBL4008265 | 0.82 | LMNA (0.41) | PTGDR2HAO1MEN1KMT2ACA12 | |
| SCHEMBL3466973 | 0.81 | CA12 (0.42) | PTGDR2KMT2ACA12CA1CA2 | |
| SCHEMBL4007168 | 0.77 | PTGDR2 (0.43) | PTGDR2MEN1KMT2ACA12CA1 | |
| SCHEMBL1856320 | 0.76 | STAT5B (0.42) | PTGDR2HSD11B1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1856318 | 0.76 | PTGDR2 (0.36) | PTGDR2HSD11B1HAO1MEN1KMT2A | |
| SCHEMBL1855707 | 0.75 | F2 (0.40) | PTGDR2HAO1KMT2ACA12CA1 | |
| SCHEMBL1863734 | 0.74 | HSD11B1 (0.47) | HSD11B1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |