Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857447 | 0.86 | STAT5B (0.43) | STAT5BTAS2R14HSD11B1CTSLCTSS | |
| SCHEMBL1856320 | 0.85 | STAT5B (0.42) | STAT5BTAS2R14HSD11B1PTGESKCNH2 | |
| SCHEMBL1857129 | 0.83 | STAT5B (0.46) | STAT5BTAS2R14HSD11B1PTGESKCNH2 | |
| SCHEMBL28588131 | 0.79 | TAS2R14 (0.55) | STAT5BTAS2R14HSD11B1CTSLCTSS | |
| SCHEMBL3724224 | 0.78 | CA12 (0.43) | STAT5BTAS2R14HSD11B1NR1H3RORC | |
| SCHEMBL12550326 | 0.78 | STAT5B (0.52) | STAT5BTAS2R14HSD11B1PTGESKCNH2 | |
| SCHEMBL4925756 | 0.76 | HTR2C (0.53) | HSD11B1NR1H3MCOLN3 | |
| SCHEMBL7707821 | 0.76 | AKT1 (0.48) | STAT5BHSD11B1CTSLCTSSCTSB | |
| SCHEMBL1010216 | 0.75 | MEP1A (0.50) | ABCB1CTSLCTSSPTGESCTSB | |
| SCHEMBL12550044 | 0.75 | STAT5B (0.49) | STAT5BTAS2R14HSD11B1NR1H3PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144890-A1 | METHOD FOR PREPARING HALOGENATED AMINES | Wyeth (US) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008098103-A1 | METHOD FOR PREPARING HALOGENATED AMINES | WYETH (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080188659-A1 | Method for Preparing Halogenated Amines | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080188659-A1 | Method for Preparing Halogenated Amines | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080188659-A1 | Method for Preparing Halogenated Amines | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188659-A1 | Method for Preparing Halogenated Amines | PNMT, ABL1, INMT | STAT5B 3704/4885TAS2R14 3551/4885HSD11B1 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.